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Impurity of Clobetasol Propionate
Clobetasol Propionate EP Impurity J / Clobetasol Propionate USP Related Compound A
Impurity
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Product Name Clobetasol Propionate EP Impurity J / Clobetasol Propionate USP Related Compound A
Product Category Impurities, Intermediates
Sub-Category Metabolites, Pharmaceutical Standards, Fine Chemicals
CAS No 1486466-31-2
Catalog Number GS.83.CLP.10
Chemical Name/Synonyms (2′R,8S,9R,10S,11S,13S,14S,16S)-4′-Chloro-5′-ethyl-9-fluoro-11-hydroxy-10,13,16-trimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3′H-spiro[cyclopenta[a]phenanthrene-17,2′-furan]-3,3′(6H)-dione; (8S,9R,10S,11S,13S,14S,16S,17R)-4′-Chloro-5′-ethyl-9-fluoro-11-hydroxy-10,13,16-trimethylspiro[6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17,2′-furan]-3,3′-dione; (17R)-4'-Chloro-5'-ethyl-9-fluoro-11ß-hydroxy-16ß-methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione; 9α-Fluoro-11β-hydroxy-16β-methyl 3-oxo-androsta-1,4-diene-17(R)-spiro-2′-[4′-chloro-5′-ethylfuran-3′(2′H)-one]; Clobetasol Propionate Related Compound A (USP);
Molecular Weight 448.95
Molecular Formula C25H30ClFO4
Purity NLT 95 %
Appearance White to off-White Solid
Solubility Dioxane, DMSO
Applications (17R)-4’-Chloro-5’-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2’(3’H)-furan]-3,3’-dione, is an impurity of Clobetasol, a topical corticosteroid, and a Glucocorticoid, used as an anti-inflammatory agent.
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