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Impurity of Lamivudine API
Lamivudine EP Impurity G
Impurity
GS.05.LAM.07.png
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Product Name Lamivudine EP Impurity G
Product Category Impurities, Intermediates
Sub-Category Metabolites, Heterocycles, Sulphur and Selenium Compounds, Pharmaceutical Standards, Antiviral Agents, Fine Chemicals, Aromatics, Amines
CAS No 160552-55-6
Catalog Number GS.05.LAM.07
Chemical Name/Synonyms Lamivudine (S)-Sulfoxide; 4-amino-1-[(2R,3S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one S-oxide; 4-amino-1-((2R,3S,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one; 2(1H)-Pyrimidinone, 4-amino-1-[(2R,3S,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-; 2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, S-oxide, [2R-(2α,3α,5α)]-; Lamivudine-S-sulfoxide; 1-[(2R,3S,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine S-oxide (USP);
Molecular Weight 245.26
Molecular Formula C8H11N3O4S
Purity NLT 95%
Appearance White Solid
Solubility DMSO, Methanol
Applications Lamivudine (S)-Sulfoxide is a metabolite of Lamivudine, a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B.
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