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Impurity of Linagliptin API
Linagliptin Inhouse Impurity 2 / 8-Bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione
Impurity
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Product Name Linagliptin Inhouse Impurity 2 / 8-Bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione
Product Category Impurities, Intermediates
Sub-Category Heterocycles, Pharmaceutical Standards, Fine Chemicals, Aromatics
CAS No 853029-57-9
Catalog Number GS.33.LNG.32
Chemical Name/Synonyms 1-[(4-Methylquinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-bromoxanthine; 8-bromo-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione; [(4-Methylquinazolin-2-yl)methyl]-3-methyl-7- (2-butyn-1-yl)-8-bromoxanthine
Molecular Weight 453.29
Molecular Formula C20H17BrN6O2
Purity NLT 95%
Appearance White to Pale Yellow Solid
Solubility DMSO, Methanol
Applications 8-Bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione is an intermediate used to prepare selective inhibitors of dipeptidyl peptidase 4 (DPP4) for potential use in the treatment of type 2 diabetes.
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