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Impurity of Loperamide Hydrochloride API
Loperamide Inhouse Impurity 8 / Diphenylacetic Acid
Impurity
GS.42.LOP.38.png
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Product Name Loperamide Inhouse Impurity 8 / Diphenylacetic Acid
Product Category Impurities, Intermediates
Sub-Category Pharmaceutical Standards, Fine Chemicals
CAS No 117-34-0
Catalog Number GS.42.LOP.38
Chemical Name/Synonyms α-Phenylbenzeneacetic Acid ; 2,2-Diphenylacetic Acid ; Diphenylethanoic Acid ; α,α-Diphenylacetic Acid ; alpha-phenylbenzeneacetic acid
Molecular Weight 212.24
Molecular Formula C14H12O2
Purity NLT 95 %
Appearance White to Creamy-White Crystalline Powder
Solubility Water
Applications Kinetic resolution of racemic 1-heteroarylalkanols by asymmetric esterification using diphenylacetic acid with pivalic anhydride and a chiral acyl-transfer catalyst is described.
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